Product Name: Recombinant Cre Recombinase-EGFP Adenovirus, Ad.CMV-Cre-EGFP
Description:
This E1/E3 deleted adenovirus expresses Cre recombinase fused to N-terminus of EGFP under the control of a CMV promoter. Cre recombinase is a type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. This adenovirus can be used for switching on or off the expression of target genes flanked by loxP sites. With EGFP the virus can be also used to determine transduction efficiency and optimize viral infection.
Titer: 1 X 1012 PFU/ml.
Purity: in vivo grade.
Size: 1000 µl
Storage Buffer: 10mM Tris-HCl pH 7.4, 137 mM NaCl, 5 mM KCl, 1mM MgCl2 with 10% glycerol
