Background
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
| |
Gene/Protein Information
Gene Name: ACVR1C
| Gene Symbol: ACVRLK7, ALK7
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Gene Name Synonyms: ACVRLK7, ALK7
| NCBI Acc#: NM_145259
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Chromosomal Location: 2q24.1
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