Background
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: AURKB
| Gene Symbol: AIK2, AIM1, AIM1, ARK2, AurB, IPL1, STK12, STK5
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Gene Name Synonyms: AIK2, AIM1, AIM1, ARK2, AurB, IPL1, STK12, STK5
| NCBI Acc#: NM_004217
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Chromosomal Location: 17p13.1
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