Background
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: AURKC
| Gene Symbol: AIE2, AIK3, AurC, STK13, auroraC
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Gene Name Synonyms: AIE2, AIK3, AurC, STK13, auroraC
| NCBI Acc#: NM_001015879
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Chromosomal Location: 19q13.43
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