Background
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: BMP2K
| Gene Symbol: BIKE, DKFZp434K0614, DKFZp434P0116, HRIHFB2017
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Gene Name Synonyms: BIKE, DKFZp434K0614, DKFZp434P0116, HRIHFB2017
| NCBI Acc#: NM_198892
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Chromosomal Location: 4q21.21
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