Background
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: BUB1
| Gene Symbol: BUB1A, BUB1L, hBUB1
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Gene Name Synonyms: BUB1A, BUB1L, hBUB1
| NCBI Acc#: NM_004336
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Chromosomal Location: 2q14
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