Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: CHUK
| Gene Symbol: IKBKA, IKKalpha, IKK1, IKKA, NFKBIKA, TCF16
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Gene Name Synonyms: IKBKA, IKKalpha, IKK1, IKKA, NFKBIKA, TCF16
| NCBI Acc#: NM_001278
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Chromosomal Location: 10q24-q25
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