Background
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: ERN1
| Gene Symbol: FLJ30999, IRE1, IRE1P, MGC163277, MGC163279
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Gene Name Synonyms: FLJ30999, IRE1, IRE1P, MGC163277, MGC163279
| NCBI Acc#: NM_001433
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Chromosomal Location: 17q24.2
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