Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
| |
Gene/Protein Information
Gene Name: EPHB2
| Gene Symbol: CAPB, DRT, EPHT3, ERK, Hek5, MGC87492, PCBC, Tyro5
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Gene Name Synonyms: CAPB, DRT, EPHT3, ERK, Hek5, MGC87492, PCBC, Tyro5
| NCBI Acc#: NM_017449
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Chromosomal Location: 1p36.1-p35
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