Background
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: IKBKE
| Gene Symbol: IKKi, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297
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Gene Name Synonyms: IKKi, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297
| NCBI Acc#: NM_014002
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Chromosomal Location: 1q32.1
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