Background
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: INSR
| Gene Symbol: CD220, HHF5
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Gene Name Synonyms: CD220, HHF5
| NCBI Acc#: NM_000208
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Chromosomal Location: 19p13.3-p13.2
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