Background
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: MAP3K14
| Gene Symbol: FTDCR1B, HS, HSNIK, NIK
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Gene Name Synonyms: FTDCR1B, HS, HSNIK, NIK
| NCBI Acc#: NM_003954
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Chromosomal Location: 17q21
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