Background
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: SMG1
| Gene Symbol: 61E3.4, ATX, KIAA0421, LIP
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Gene Name Synonyms: 61E3.4, ATX, KIAA0421, LIP
| NCBI Acc#: NM_015092
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Chromosomal Location: 16p12.3
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