Background
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: PRKD2
| Gene Symbol: HSPC187, PKD2
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Gene Name Synonyms: HSPC187, PKD2
| NCBI Acc#: NM_001079880
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Chromosomal Location: 19q13.3
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