Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: RPS6KA3
| Gene Symbol: CLS, HU3, ISPK1, MAPKAPK1B, MRX19, RSK, RSK2, S6Kalpha3, p90RSK2, pp90RSK2
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Gene Name Synonyms: CLS, HU3, ISPK1, MAPKAPK1B, MRX19, RSK, RSK2, S6Kalpha3, p90RSK2, pp90RSK2
| NCBI Acc#: NM_004586
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Chromosomal Location: Xp22.2-p22.1
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