Background
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: SCYL1
| Gene Symbol: GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP
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Gene Name Synonyms: GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP
| NCBI Acc#: NM_020680
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Chromosomal Location: 11q13
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