Background
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC Chromatography.
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Gene/Protein Information
Gene Name: sentrin/SUMO-specific protease 7 isoform 2
| Gene Symbol: SENP7
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Gene Name Synonyms: KIAA1707; MGC157730
| NCBI Acc#: NM_001077203
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