Background
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: TRIB3
| Gene Symbol: C20orf97, NIPK, SINK, SKIP3, TRB3
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Gene Name Synonyms: C20orf97, NIPK, SINK, SKIP3, TRB3
| NCBI Acc#: NM_021158
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Chromosomal Location: 20p13-p12.2
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