Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
| |
Gene/Protein Information
Gene Name: tuberous sclerosis 2 isoform 4
| Gene Symbol: TSC2
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Gene Name Synonyms: FLJ43106; LAM; TSC4
| NCBI Acc#: NM_001077183
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