Background
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
|
Purification Method: FPLC
| |
Gene/Protein Information
Gene Name: AKT3
| Gene Symbol: DKFZP434N0250, PKBG, PRKBG, RACPKgamma, RACgamma, STK2
|
Gene Name Synonyms: DKFZP434N0250, PKBG, PRKBG, RACPKgamma, RACgamma, STK2
| NCBI Acc#: NM_005465
|
Chromosomal Location: 1q43-q44
| |