Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
|
Purification Method: FPLC
| |
Gene/Protein Information
Gene Name: SRC
| Gene Symbol: ASV, SRC1, cSRC, p60Src
|
Gene Name Synonyms: ASV, SRC1, cSRC, p60Src
| NCBI Acc#: NM_005417
|
Chromosomal Location: 20q12-q13
| |
