Background
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM].
Product Information
Source: HEK293
| Purity: >95% by SDS-PAGE analysis
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: WNK3
| Gene Symbol: KIAA1566, PRKWNK3
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Gene Name Synonyms: KIAA1566, PRKWNK3
| NCBI Acc#: NM_020922
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Chromosomal Location: Xp11.23-p11.21
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