Background
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
Product Information
Source: E coli; insect cells; or mammalian cells: 293, CHO
| Purity: Greater than 95% as determined by RP-HPLC or SDS-PAGE analysis.
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: atlastin GTPase 1 isoform b
| Gene Symbol: ATL1
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Gene Name Synonyms: AD-FSP; atlastin1; FSP1; GBP3; SPG3; SPG3A
| NCBI Acc#: NM_001127713
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Availability
Custom Expression: 4 to 10 weeks
