Background
This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq].
Product Information
Source: E coli; insect cells; or mammalian cells: 293, CHO
| Purity: Greater than 95% as determined by RP-HPLC or SDS-PAGE analysis.
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Purification Method: FPLC
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Gene/Protein Information
Gene Name: zinc finger, CSL domain containing 2 isoform 2
| Gene Symbol: DPH3
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Gene Name Synonyms: DELGIP; DELGIP1; DESR1; DPH3A; KTI11;
| NCBI Acc#: NM_001047434
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Availability
Custom Expression: 4 to 10 weeks
